BLU 532E - Applied Inform.in Struc.Biol.

Course Objectives

1) Introducing structural basics of biological phenomena
2) Introducing types, representation, visualization and sources of structural biology data
3) Introducing informatics approaches that are based on sequence and structure of biological
macromolecules
4) Introducing methods that analyze sequence-structure-function relationships

Course Description

Structural bioinformatics, Fundamentals of protein, DNA and RNA structure, Structure-based biological databases and online services, Visualization of Biomolecules, Sequence alignments, Structure alignments and classification, Protein secondary and three-dimensional structure prediction, Nucleic acid secondary and three-dimensional structure prediction, Protein-protein interaction modeling, Structural bioinformatics for membrane proteins