MBG 636E - Epigenetics

Course Objectives

1. To provide students with scientific knowledge and skills epigenetic mechanisms and their
relations with gene expression regulations.
2. To help students to develop skills in scientific literature research and presentation the relation
between epigenetic dysfunctions and human diseases.
3 To provide experience in oral and written communication.

Course Description

DNA methylation, histone modifications, chromatin re-modeling, genomic imprinting, X-inactivation, role of methylation in cancer development and importance of miRNAs, laboratory and computational analysis, epigenetic reprogramming in stems cells and importance of epigenetic regulation during mammalian development, immune cells functioning and the role of the loss of epigenetic control in the development of diseases.