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KIM 629
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Course Weekly Lecture Plan
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Course Weekly Lecture Plan
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Course Weekly Lecture Plan
Week
Topic
1
1- Definition of free radicals, properties, stabilities, reactivities and kinetics
2
2- Radicals centered on an atom other than carbon
3
3-Reactions and mechanisms of free radicals I (production methods of free radicals, radical-radical reactions, substitution reactions)
4
4-Reactions and mechanisms of free radicals II (production methods of free radicals, radical-radical reactions, substitution reactions)
5
5-Reactions and mechanisms of free radicals III (addition and fragmentation reactions of free radicals)
6
6-Reactions and mechanisms of free radicals IV (cyclizations and rearrangement reactions of radicals)
7
7-Aromatic substitution reactions of free radicals
8
8-Reactions of charged radicals and free radicals in biochemistry
9
9-How to prove that a reaction is a radical process
10
10-Applications in synthesis I (functionalization of C-H bond, transformation of functional groups, additions of multiple bonds and coupling reactions)
11
11-Applications in synthesis II (Reaction of Barton-McCombie for nucleosides and sugars, Barton Decarboxylation reaction, free radical reactions with metal hydride)
12
12-Applications in polymer chemistry (free radical polymerization) I
13
13-Applications in polymer chemistry (controlled/living radical polymerization) II
14
14-Current advances
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