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KIM 623E - Stereochemistry and Conformational Analysis

Course Objectives

1. Providing the knowledge and in depth understanding between the stereochemistry and conformation of organic molecules and their properties and behaviour.
2. Interpreting the results of the methods of quantum chemistry in the context of organic reactions.
3. Evaluating the relative importance of steric and stereo electronic effects on pathways of organic reactions.
4. Studying the consequences of different stereochemical and conformations on the chemical reactivity and on the mechanisms of organic and bioorganic reactions.
5. Introducing the modern methods of stereochemical and conformational analysis.

Course Description

Molecular structure and symmetry; stereochemical and conformational behavior of acyclic, cyclic, heterocyclic, polycyclic compounds, natural macromolecules such as carbohydrates and proteins and synthetic macromolecules such as polypropylene, methyl methacrylate; stereochemistry and conformational analysis related to reaction mechanisms, case study of chemical transformations based on modern concepts of conformational analysis; examples of reactions like additions, cycloadditions, molecular rearrangements or other chemical reactions, several aspects of modeling towards biocatalysts; modern methods used for the stereochemical and conformational analysis; the principles of conformational analysis and their applications in organic chemistry.

Course Coordinator
Oya Atıcı
Course Language
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