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Course Information

Course Name
Turkish Nukleik asit ve protein biyokimyası
English Nucleic Acids&Protein Biochemi
Course Code
MBG 621E Credit Lecture
Semester 1
3 3 - -
Course Language English
Course Coordinator Nevin Gül Karagüler
Course Objectives The purpose of this course is to make students knowledgeable about basic and essential concepts of nucleic acids and proteins which are the 4 of macromolecules of living organisms at advanced level
Course Description Physical properties of nucleic acids, isolation methods, principles of DNA reassociation and RNA hybridization experiments, genome complexities, recombinant DNA procedures and nucleotide sequence analysis, DNAs and RNAs as catalysists. Interaction of nucleic acids with proteins such as repressors, restriction and modification enzymes, RNA recognition. The relationship between protein structure and function. Topics include binding specificity, cooperativity and allostery, protein folding, evolution and macromolecular assembly, sequence homology and prediction of structure.
Course Outcomes
Required Facilities
Textbook R.H. Sarma, M.H. Sarma. Structure and Function : Nucleic Acids, Proteins, 1992. Adenine Pr; ISBN: 0940030365.
2 Harald Tschesche. Modern Methods in Protein-And Nucleic Acid Research. 1991. Walter De Gruyter; ISBN: 3110122758.
3 David L. Nelson, Michael M. Cox. Lehninger: Principles of Biochemistry 1991.Worth Publishers; ISBN-13: 978-0-7167-7108-1.
4 Felicia Y.H. Wu, Cheng-Wen Wu. Structure and Function of Nucleic Acids and Proteins. 1990. Amazon books. ASIN: 0881676780.
5 Joseph N.M. Mol, Alexander R. Van Der Krol. Antisense Nucleic Acids and Proteins. 1991. Marcel Dekker; ISBN: 0824785169.
Other References
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